SEXUALLY TRANSMITTED DISEASES - present in birth canal...

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SEXUALLY TRANSMITTED DISEASES Gonorrhea - Neisseria gonorrhea Gram neg. diplococci, bean-shaped with indented sides facing Virulence: Encapsulated, pili, endotoxins, catalase, intracellular parasite. Transmission: Direct contact - sexual contact P/E: M.m. of genitourinary tract: i.e., vagina, urethra in males. Disease: Adheres to and invades m.m. causes damage to m.m. lining inflammation. In males usually more acute - painful voiding, purulent discharge from urethra. Can spread to vas deferens, testes causing scarring, infertility. Scarring in urethra leads to frequent UTI's. In females infection often low grade, asymptomatic (chronic). Spreads to uterus, cervix, fallopian tubes, ovaries. Scarring of fallopian tubes sterility. Identification: Direct smear exudate - observe Gram neg. diplococci in PMN's (fig. pg. 606), follow with culture. Complications: Gonococcal Opthalmia Neonatorum Infection of eyes of newborn - exposed during birth if organisms
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Unformatted text preview: present in birth canal. Causes destruction, scarring cornea → blindness. Prevent: treat eyes with 1% silver nitrate, antibiotics following birth. In adults, bacteria can be transferred from genitals to eyes by hands, also see fig. pg. 606. Nongonococcal Urethritis (NGU) - Chlamydia trachomatis Virulence: Obligate intracellular parasite (cannot produce ATP, leaky membrane) Transmission: Sexual intercourse P/E: m.m. genitourinary tract Disease: Resembles gonorrhea, but milder. Infects m.m. of vagina, urethra. Low grade, scanty, watery discharge. May also be asymtomatic, causing chronic infections. Can eventually cause scarring and infertility in males and females. Complication: In pregnant females, can infect fetus causing death, congenital deformities. NGU is becoming more prevalent than any other sexually-transmitted disease....
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