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Syphilis - probably develops due to delayed...

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Syphilis - Treponema pallidum Gram neg. spiral, very small, tightly-coiled Transmission: Direct contact - sexual intercourse, occasionally kissing. P/E: M.m. genitourinary tract (occas. mouth). Disease: Inc. pd. - 3 wks. ave. Disease occurs in stages: 1) Primary stage : Usually single lesion - chancre - ulcer-like, about 1/2 inch dia., asymptomatic . Self limiting - heals after several (4-6) wks. May remain free of symptoms 2 wks. - several mo. before next stage. 2) Secondary stage : Multiple lesions occurring on skin, m.m. on face, in and around mouth, palms of hands, soles of feet, external genitalia. Heals in few wks., but can recur over period of 2 - 5 yrs. Accom. by fever, enlarged lymph nodes, malaise. Then individual may remain free of symptoms (latent) 5 - 40 yrs. 3) Tertiary stage : Internal lesions produced in bone, cardiovascular, CNS. Called gummas - abscess-like lesions with central rubbery mass surrounded by connect. tissue -
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Unformatted text preview: probably develops due to delayed hypersensitivity. Leads to crippling, aneurysm, insanity, paralysis. In this stage not very infectious. This stage seldom seen today due to effective treatment. Complications: Can cross placenta, infecting fetus → congenital syphilis. Causes congenital deformities or death. Identification: Demonstration organism in exudate from lesions, serological tests. Organism cannot be grown in lab. Genital Warts (Condylomas) - Papilloma viruses Transmission: Sexual intercourse; increased incidence in sexually-active teens, young adults. Disease: Warts occur on penis, anus or perineum in males, in females - vagina, cervix, perineum, anus. Causes irritation, itching, can become infected with bacteria. If persist can become malignant. Complications: Infants can become infected during delivery. In females ↑ cervical cancer....
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