706_F06pset5 - 7.06 Fall 2006 11/1/06 Problem Set 5 1. a....

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7.06 Fall 2006 PS 5 1 of 3 7.06 Fall 2006 11/1/06 Problem Set 5 1. a. Describe the structure and functions of the three types of cytoskeletal filaments described in class: What types of molecules compose the different types of filaments? What are the functions of each? b. Describe three similarities in the structural/functional properties of actin and tubulin. c. Treatment of cells with taxol causes cell cycle arrest in mitosis. Why? How does taxol affect the microtubules? 2. What happens to a microtubule that loses its “GTP cap”? 3. You are interested in studying the properties of skeletal muscle using mouse as a model system. a. You notice the dead mice are stiff/in rigor mortis. Based on what you know about actin/myosin interaction in muscles, explain the molecular basis of rigor mortis: b. You isolate tissue from these stiff mice and treat it with a non-hydrolyzable ATP analog. What do you expect to happen to the muscle and why? 4.
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This note was uploaded on 01/23/2012 for the course BIOLOGY lsm1301 taught by Professor Seow during the Spring '11 term at National University of Singapore.

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706_F06pset5 - 7.06 Fall 2006 11/1/06 Problem Set 5 1. a....

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