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Unformatted text preview: = Leukocidins, produced by species of Staphylococcus and Streptococcus, can cause destruction of white blood cells = Hemolysins cause lysis of red blood cells = Coagulases, which promote clot formation, may aid pathogenicity by isolating the pathogen from host defenses = On the other hand, streptokinase, produced by some Streptococcus strains, may contribute to virulence by causing clots to break down, releasing the pathogen from isolation = Hyalurinidase breaks down hyaluronic acid, a polysaccharide that helps to hold together connective tissues, helping the pathogen to spread within tissues = Collagenase breaks down collagen, a protein of connective tissue- Many extracellular bacteria have been shown to enter host cells through the activity of surface protein invasins (Tortora et al. Figure 15.2)...
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- Fall '09