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Systems Microbiolo12 - • Cells from a huge variety of...

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Systems Microbiology 􀂃 Agrobacteria causes plant diseases, with galls (tumors) that look a lot like the nodules created by Rhizobia . • However, this is parasitism, not mutual symbiosis • The agrobacteria causes a kind of genetic engineering, inserting its own DNA and changing the plant development • This inserted DNA includes oncogenes • The DNA also includes genes for opine synthesis, which the bacteria get the plant to produce and feed to them • The bacteria can thus naturally transform the plant cells to turn them into an opine factory for themselves 􀂃 People use this same method (Ti plasmids, plus some intermediate factors) for genetic engineering in plants • Transgene delivery system based on the Ti plasmid • Segregation of the transgene – Mendelian
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Unformatted text preview: • Cells from a huge variety of species can be modified in this way – plant, fungal, even human ° A lot of people have problems with this kind of genetic modification, but there are also a lot of benefits • Most of the corn grown in the US is genetically modified • However, once you get these genetically-modified plants out into the field, it’s hard to keep them contained – the pollen spreads from farm to farm • The effects of this on plant diversity and gene transfer could be worrisome • There are intellectual property issues involved – what happens when a company produces a genetically-modified plant and then it turns up on other farms via pollen • Also other controversies of ethics, labeling, society…...
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