Systems Microbiolo19

Systems Microbiolo19 - Systems Microbiology o You can...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Systems Microbiology o You can recognize the genetic code from the start and stop sites – this lets you know where there might be gene sites o You have to figure out what the right reading frame are – there are always three possible frames. ° You can use a program to find open reading frames o Gene finding – current methods. ° Homology method/Extrinsic method – use other genomes that have already been sequenced, and compare ° Gene prediction method/Intrinsic method – look at the codon content o Content sensors and gene prediction tools – there are many different programs o Demonstration: Prof. Delong pastes a DNA sequence (around 70 kilobase pairs) from a marine microorganism into a sample commercial program on the web ° It gives back a list of possible genes, with around one gene for every thousand base pairs o These possible genes are then pasted into another program: BLAST. ° It compares the sequences with known genes
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/24/2012 for the course MCB MCB2010 taught by Professor Smith during the Fall '09 term at Broward College.

Ask a homework question - tutors are online