Systems Microbiolo42

Systems Microbiolo42 - • Read Chapter 8.13 in the text to...

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Systems Microbiology ° Reading for today: Chapter 5 and Chapter 17 (533-555) ° Reading for next class: Chapter 6 – Microbial Growth ° For today: Bioenergetics and physiological diversity o Finish up chemotaxis o Basic modes of energy generation o Thermodynamics of growth o Diversity in energy acquisition ° Chemotaxis o Flagella rotate counterclockwise, driving the microbe forward ° When it switches to clockwise, the flagella all fly apart – change location – tumble ° To choose direction, they can’t really sense space, but over time they sense the concentration of particular chemicals • They do this with receptors on their surface • Che A auto phosphorylates Che Y to cause motor to drive, in the presence of the right concentration • As the concentration rises over time, the cell makes a net motion along the concentration gradient • This is a complex feedback mechanism • A fully methylated receptor is not able to respond to an attractant
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Unformatted text preview: • Read Chapter 8.13 in the text to understand this o Pili – another structure that’s involved in attachment and motility ° For growth and biosynthesis cells need: o Energy, in the form of ATP o Reducing power, in the form of NADH o Basic macronutrients: C, N, P, S (nmol to mmol in the environment) Mg ++ , K + , Na + , Ca ++ o Micronutrients: Fe, Mn, B, Cr, Cu, Mo, Ni, Se, W, V, Zn ° Where do organisms get their energy? o Light, or chemical energy (phototrophs vs. chemotrophs) o Both exist in the microbial world o Microbial chemotrophs: chemolithotrophs (oxidize inorganic compounds) vs. chemoorganotrophs (oxidize organic compounds) o Microbial chemoorganotrophs can reduce elements other than oxygen. They can use Iron, or Nitrate. o In general, microbes are different from eukaryotes because they can oxidize and reduce a much broader variety of different chemicals ° Free energy and bioenergetics...
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This note was uploaded on 01/24/2012 for the course MCB MCB2010 taught by Professor Smith during the Fall '09 term at Broward College.

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Systems Microbiolo42 - • Read Chapter 8.13 in the text to...

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