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Unformatted text preview: Systems Microbiology Cell membranes: phospholipid bilayer o Main permeability barrier o Embedded integral membrane proteins communication, transport o Membrane structure Bacteria, eukaryotes Archaea o Archaea can still make lipid bilayers though sometimes they hook them directly together, making a lipid monolayer. This is much more structurally rigid. This is never found in bacteria or eukaryotes. o Membranes act as a protein anchor. o Also energy conservation protein motive force. o Membrane permeability to various molecules: Simple transport: let a proton down the gradient in order to move things. Group translocation: chemical modification of transported substance driven by phosphoenolpyruvate. ABC system: periplasmic binding proteins are involved and energy comes from ATP. o Transport method: Uniporter: one thing comes in. Antiporter: one thing in, one out....
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