Systems Microbiolog3

Systems Microbiolog3 - ° They might cause infection but...

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Systems Microbiology ° Some R-factors reside on the plasmid, so that they can be easily transferred from one microbe to another o Healthcare-associated infections (HAIs) o Methicillin-resistant Staphylococcus aureus N315 ° Penicillin binding protein ° Terminology o “Normal flora” – it’s normative (most people have it), and “flora” means plant growth ° Clearly, this is imprecise, since microbes in our gut aren’t plants ° Microbiota is a better term o Commensal ° Symbiotic – the biology is interwoven, and both we and the microbes benefit ° This is colonization (as opposed to infection) o Pathogen ° Not all pathogens cause disease in all individuals
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Unformatted text preview: ° They might cause infection but not illness ° If you’re infected with TB, you’re not going to die from TB – you’re going to die from the infection and disease that it causes ° What kinds of problems the microbe might or might not cause have to do with the virulence of the strain, your own immune reaction, environmental factors, age, etc. ° If you maintain a stable relationship with the microbe, regardless of whether it causes disease, it is an infection o Opportunistic pathogens ° They take advantage of defects in host defenses, so that people with some kind of immodeficiency can get much much sicker...
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This note was uploaded on 01/24/2012 for the course MCB MCB2010 taught by Professor Smith during the Fall '09 term at Broward College.

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