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The Citric Acid Cycl1 - • Three molecules of NAD were...

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The Citric Acid Cycle Reaction 7: Fumarase In this reaction, the enzyme fumarase catalyzes the addition of a water molecule to the fumarate in the form of an –OH group to yield the molecule L- malate. Figure %: Reaction 7. Reaction 8: Malate Dehydrogenase In the final reaction of the citric acid cycle, we regenerate oxaloacetate by oxidizing L–malate with a molecule of NAD to produce NADH. Figure %: Reaction 8. Conclusion We have now concluded our discussion of the reactions that compose the citric acid cycle. It is helpful at this point to take a minute to take stock of what the citric acid cycle has generated from one acetyl-CoA molecule. The acetyl-CoA, has been oxidized to two molecules of carbon dioxide.
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Unformatted text preview: • Three molecules of NAD were reduced to NADH. • One molecule of FAD was reduced to FADH2. • One molecule of GTP (the equivalent of ATP) was produced. Keep in mind that a reduction is really a gain of electrons. In other words, NADH and FADH2 molecules act as electron carriers and are used to generate ATP in the next stage of glucose metabolism, oxidative phosphorylation. In the next SparkNote on Oxidative Phosphorylation and the electron transport chain , we will learn what processes take place to ultimately derive the the majority of the ATP we need to fuel our daily activity....
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