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Unformatted text preview: Reaction 1: Citrate Synthase The first reaction of the citric acid cycle is catalyzed by the enzyme citrate synthase. In this step, oxaloacetate is joined with acetyl-CoA to form citric acid. Once the two molecules are joined, a water molecule attacks the acetyl leading to the release of coenzyme A from the complex. Figure %: Reaction 1. Reaction 2: Acontinase The next reaction of the citric acid cycle is catalyzed by the enzyme acontinase. In this reaction, a water molecule is removed from the citric acid and then put back on in another location. The overall effect of this conversion is that the OH group is moved from the 3' to the 4' position on the molecule. This transformation yields the molecule isocitrate. Figure %: Reaction 2....
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