Chap 47 notes

Chap 47 notes - Chapter 47 Learning Objective 4 * Compare...

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Chapter 47 Learning Objective 4 * Compare four types of endocrine signaling Types of Endocrine Signaling (Fig 48-3) Local Regulators * Some are considered hormones * use autocrine and paracrine signaling * Growth factors (paracine, autocrine) * peptides stimulate cell division, development * Some implicated in oncogenesis * Prostaglandins (paracrine) * help regulate many metabolic processes * stimulate smooth muscle cells to relax and contract * Take part in inflammation process Learning Objective 5 * Compare the mechanism of action of small, lipid-soluble hormones with that of hydrophilic hormones * Include the role of second messengers, such as cyclic AMP Small, Lipid-Soluble Hormones * Steroid hormones, thyroid hormones * Small and hydrophobic and therefore pass through plasma membrane * combine with cytosolic or nuclear receptors in target cell; highly specific (lock and key) * Hormone–receptor complex * activates or represses transcription of messenger RNA coding for specific proteins
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Chap 47 notes - Chapter 47 Learning Objective 4 * Compare...

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