Chap 50 notes

Chap 50 notes - Chapter 50 KEY CONCEPTS * In humans and...

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Chapter 50 KEY CONCEPTS * In humans and other mammals, reproduction is regulated by hormones produced by the hypothalamus, pituitary gland, and gonads Learning Objective 5 * Trace the development of a human egg and its passage through the female reproductive system until it is fertilized Oogenesis 1 * In the ovaries * Oogonia * ~ million oogonia present at birth differentiate into primary oocytes prenatally * At birth; in prophase of first meiotic division * Enter resting phase * Follicle consists of a primary oocyte plus granulosa cells surrounding it Oogenesis 2 * As follicle grows (e.g. at puberty) in response to FSH: * connective tissue cells surrounding granulosa cells form layer of theca cells * As follicle matures primary oocyte completes first meiotic division, giving rise to secondary oocyte (moves through second meiotic division, to metaphase II) and a polar body * Secondary oocyte remains in metaphase II until fertilized * Upon fertilization, becomes ovum and polar body then divides to form two polar bodies
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Chap 50 notes - Chapter 50 KEY CONCEPTS * In humans and...

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