Lecture15C.elegans

Lecture15C.elegans - saving the best for last . . ....

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Unformatted text preview: saving the best for last . . . Caenorhabditis elegans the ease of propagating C. elegans E. coli Caenorhabditis elegans : g gonad h hypodermis I intestine m muscle nc nerve cord anatomy of C. elegans C. elegans sexes: C. elegans life cycle C. elegans genome molecular and genetic data is stored in public databases: http://www.wormbase.org/ http://elegans.swmed.edu/ 97Mb 22,227 genes 1 gene/5 kb genes have on average 6 introns 27% of genome resides in exons 42% of genes have distant matches 34% match only nematode proteins The C. elegans Sequencing Consortium, 1998 invariant development makes C. elegans an excellent model for investigating mechanisms of development E M S 2002 Nobel Prize in Physiology or Medicine male = X0 hermaphrodite/female = XX Spermatocytes Prolifera;ve Zone Transi;on Zone Pachytene Sperm Distal Tip Prolifera;ve Zone Transi;on Zone Pachytene Diplotene Diakinesis Oocytes Sperm Embryos Distal Tip Apopto;c Nuclei Meiosis II Meiosis I meiosis Replication Pairing Crossovers Formed C. elegans: gonad and germline development sperm oocytes meiotic prophase mitotic blue = DAPI ; red = SYP-1 Zoom...
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This note was uploaded on 01/25/2012 for the course MCB 160L160L taught by Professor Venkatesansundaresan during the Fall '11 term at UC Davis.

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Lecture15C.elegans - saving the best for last . . ....

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