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pg 7 - Moderate and high doses of red wine yielded a...

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The subjects consisted of 22 healthy, non-smoking men with a mean age of 23+/-1.8 years, a BMI of 24+/-2.3kg/m^2, and a total cholesterol of 4.2+/- 0.8mmol/l. None of the subjects were on medication and all of the subjects were instructed to avoid caffeine and tobacco. Each subject was randomly assigned either a moderate dose of red wine with .5 g/kg of ethanol, a high dose of red wine with 1 g/kg of ethanol, or an equal volume of de-alcoholized red wine. The subjects had their coronary flow reserve measured 30 minutes before and after each dose of moderate, high, and de-alcoholized red wine.
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Unformatted text preview: Moderate and high doses of red wine yielded a significant increase in coronary flow reserve, from 3.8+/- 1.4 to 4.5+/-1.4 and 4.0+/-1.2. However, de-alcoholized red wine had no significant effects on coronary flow reserve. There was also a significant increase in antioxidant capacity after the subjects consumed red wine, but no effect when de-alcoholized red wine was consumed. This study demonstrates that a moderate dose of red wine, but not de-alcoholized red wine, not only increases coronary flow reserve, but also plasma antioxidant capacity....
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