Ch1-Cell

Ch1-Cell - CELL ADAPTATIONS CELL ADAPTATIONS CELL INJURY...

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Unformatted text preview: CELL ADAPTATIONS CELL ADAPTATIONS CELL INJURY CELL INJURY CELL DEATH CELL DEATH OBJECTIVES Understand the 3 main anatomic concepts of disease--- Degenerative, Inflammatory, Neoplastic Understand the concepts of cellular growth adaptations--- Hyperplasia, Hypertrophy, Atrophy, Metaplasia Understand the factors of cell injury and death--- O2, Physical, Chemical, Infection, Immunologic, Genetic, Nutritional OBJECTIVES Understand the pathologic mechanisms at the SUB-cellular level--- ATP, Mitochondria, Ca++, Free Radicals, Membranes Understand and differentiate the concepts of APOPTOSIS and NECROSIS Understand SUB-cellular responses to injury--- Lysosomes, Smooth endoplasmic reticulum, Mitochondria, Cytoskeleton OBJECTIVES Identify common INTRA-cellular accumulations--- Fat, Hyaline, CA+ +, Proteins, Glycogen, Pigments Understand aging and differentiate the concepts of preprogrammed death versus wear and tear. PATHOLOGY Pathos (suffering) Logos PATHOLOGY GENERAL SYSTEMIC PATHOLOGY ETIOLOGY (Cause) PATHOGENESIS (Insidious development) MORPHOLOGY (ABNORMAL ANATOMY) CLINICAL EXPRESSION ETIOLOGY Cause vs. Risk Factors PATHOGENESIS sequence of events from the initial stimulus to the ultimate expression of the disease MORPHOLOGY Abnormal Anatomy Gross Microscopic Radiologic Molecular CLINICAL EXPRESSION Ironically, even though clinical expression is not often present in subclinical diseases, it is the pathos of pathology. Most long term students of pathology, like myself, will strongly agree that the very best way for most minds to remember, or identify, or understand a disease is to associate it with a morphologic...
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This note was uploaded on 01/25/2012 for the course PDBIO 305 taught by Professor Woods,a during the Fall '08 term at BYU.

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Ch1-Cell - CELL ADAPTATIONS CELL ADAPTATIONS CELL INJURY...

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