Ch8-Infectious

Ch8-Infectious - INFECTIOUS INFECTIOUS DISEASES DISEASES...

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INFECTIOUS INFECTIOUS DISEASES DISEASES
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Categories of INFECTIOUS AGENTS Prions * Viruses Bacteriophages, Plasmids, Transposons * Bacteria Chlamidiae, Rickettsiae, Mycoplasmas * Fungi: Yeasts, Hyphae Parasites: Protozoa, Worms, Arthropods
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Classes of Human Pathogens and Their Habitats Taxonomic Size Site of Propagation Sample Species Disease Viruses 20–300 nm Obligate intracellular Poliovirus Poliomyelitis Chlamydiae 200–1000 nm Obligate intracellular Chlamydia trachomatis Trachoma, urethritis Rickettsiae 300–1200 nm Obligate intracellular Rickettsia prowazekii Typhus fever Mycoplasmas 125–350 nm Extracellular Mycoplasma pneumoniae Atypical pneumonia Bacteria 0.8–15 µm Cutaneous Staphylococcus aureus Wound Mucosal Vibrio cholerae Cholera Extracellular Streptococcus pneumoniae Pneumonia Facultative intracellular Mycobacterium tuberculosis Tuberculosis Fungi 2–200 µm Cutaneous Trichophyton sp. Tinea pedis (athlete's foot) Mucosal Candida albicans Thrush Extracellular Sporothrix schenckii Sporotrichosis Facultative intracellular Histoplasma capsulatum Histoplasmosis Protozoa 1–50 µm Mucosal Giardia lamblia Giardiasis Extracellular Trypanosoma gambiense Sleeping sickness Facultative intracellular Trypanosoma cruzi Chagas disease Obligate intracellular Leishmania donovani Kala-azar Helminths 3 mm–10 m Mucosal Enterobius vermicularis Enterobiasis Extracellular Wuchereria bancrofti Filariasis Intracellular Trichinella spiralis Trichinosis
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PRIONS, “BSE” (Cows), “CJD”, Kuru (Humans) NON-Nucleic Acid PrP = Prion Protein Diagnostic Test : NL-COW MAD-COW http://www.youtube.com/watch?v=w5aAPEY IL9A
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B ovine S pong iform E ncephalitis, C reutsfeldt- J akob D isease
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VIRUSES Less than ½ micron, usually MUCH less DNA/RNA “CORE” (genome) Protein “CAPSID” (protein –NA “coat”) Sometimes a lipid “ENVELOPE” Limited number of genes coding for all other structures NO consistent naming system
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Respiratory Adenovirus Adenoviridae DS DNA Upper and lower respiratory tract infections, conjunctivitis, diarrhea Rhinovirus Picornaviridae SS RNA Upper respiratory tract infection Coxsackievirus Picornaviridae SS RNA Pleurodynia, herpangina, hand- foot-and-mouth disease Coronavirus Coronaviridae SS RNA SARS, URIs Influenza viruses A, B Orthomyxoviridae SS RNA Influenza Respiratory syncytial virus Paramyxoviridae SS RNA Bronchiolitis, pneumonia
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Digestive Mumps virus Paramyxoviridae SS RNA Mumps, pancreatitis, orchitis Rotavirus Reoviridae DS RNA Childhood diarrhea Norwalk agent Caliciviridae SS RNA Gastroenteritis Hepatitis A virus Picornaviridae SS RNA Acute viral hepatitis Hepatitis B virus Hepadnaviridae DS DNA Acute or chronic hepatitis Hepatitis D virus Viroid-like SS RNA With HBV, acute or chronic hepatitis Hepatitis C virus Flaviviridae SS RNA Acute or chronic hepatitis Hepatitis E virus Norwalk-like SS RNA Enterically transmitted hepatitis
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Systemic with Skin Eruptions Measles virus ParamyxoviridaeSS RNA Measles (rubeola) Rubella virus Togaviridae SS
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This note was uploaded on 01/25/2012 for the course PDBIO 305 taught by Professor Woods,a during the Fall '08 term at BYU.

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Ch8-Infectious - INFECTIOUS INFECTIOUS DISEASES DISEASES...

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