Ch19-Pancreas

Ch19-Pancreas - PANCREAS OBJECTIVES • Understand the...

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Unformatted text preview: PANCREAS OBJECTIVES • Understand the etiology/risk factors, pathogenesis, morphology, clinical features and outcome of pancreatic inflammations and neoplasms Chapter 19 Posterior view of duodenum/pancreas Arterial supply and venous drainage of the pancreas and spleen Lymphatic drainage of the distal pancreas and spleen Hepaticopancreatic ampulla (Ampulla of Vater) Pancreatic Enzymes • Amylase • Lipase • DNA-ase • RNA-ase • Zymogens: Trypsinogen Chymotrypsinogen, Procarboxypeptidase A, B PANCREAS DISEASES • Congenital • Inflammatory – Acute – Chronic • Cysts • Neoplasms Congenital • Agenesis (very rare) • Pancreas Divisum (failure of 2 ducts to fuse) (common) • Annular Pancreas (pancreas encircles duodenum) (rare) • Ectopic Pancreas (very common) PANCREATITIS • ACUTE (VERY SERIOUS) • CHRONIC (Calcifications, Pseudocyst) CONSEQUENCES of ACUTE and CHRONIC pancreatitis ACUTE PANCREATITIS • ALCOHOLISM • Bile reflux • Medications (thiazides) • Hypertriglyceridemia, hypercalcemia • Acute ischemia • Trauma, blunt, iatrogenic • Genes: PRSS1, SPINK1 • Idiopathic, 10-20% CLINICAL FEATURES...
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Ch19-Pancreas - PANCREAS OBJECTIVES • Understand the...

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