Bone+health_osteo+S10_Student

Bone+health_osteo+S10_Student - Bone health Nutrients...

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Bone health
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Nutrients involved in bone health Vitamins Vitamin D (pp. 363-368)) Vitamin K (pp. 370-371) Minerals Calcium (pp.400-406) Phosphorus (pp. 406-407) Magnesium (pp. 407-409) Fluoride (pp.442-443)
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Vitamin D Calciferol Different from all the other nutrients not essential Precursor from sun or food needs to be activated by: 1.liver 2.kidney
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Activation of vitamin D
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Vitamin D function Actually a hormone Target organs: intestines kidneys bones
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Vitamin D in bone growth Maintains blood concentrations of calcium and phosphorus 1. Enhances Ca & P absorption from GI tract 2. Enhances Ca & P reabsorption from kidneys Enhances mobilization of Ca & P from bones into blood
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Risk factors for vitamin D deficiency dark skin breastfeeding without supplementation Lack of sunlight Drinking unfortified milk Text
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Vitamin D deficiency calcium absorption impaired Ca deficiency despite sufficient intake Rickets Breast-fed, black children at highest risk Bones become weak legs bow out when weight bearing
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Vitamin D deficiency in adults osteomalacia Defect in mineralization of bone framework Bones become soft, flexible, brittle, and deformed Painful osteoporosis Calcium loss from bones Fractures
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Bone health in elderly Decreased ability of skin, liver and kidneys to make & activate vitamin D Decreased milk intake Less time spent outside More covered up when outside
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Vitamin D deficiency may be associated with increased risk of Some cancers Some autoimmune diseases (ex: RA, MS) Hypertension (HTN) Some infectious diseases
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Vitamin D toxicity Upper level: 50 mcg/day Most likely nutrient to be consumed in excessive amounts Caution with supplements Excess vitamin D increased calcium level soft tissue calcification Kidney stones Calcified arteries
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This note was uploaded on 01/26/2012 for the course NTDT 200 taught by Professor Aljadir during the Fall '08 term at University of Delaware.

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Bone+health_osteo+S10_Student - Bone health Nutrients...

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