nwk2-1 - Elongation: RNA polymerase builds the RNA 2.4....

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Elongation: RNA polymerase builds the RNA 2.4. Termination sequences: form hairpin loops in the RNA that destabilize RNA polymerase, and/or rho protein binds to a recognition site just upstream of the hairpin loop, moves downwards & separates the DNA & RNA. Fig. 8.11c In prok., no further modification of RNA, though 5 end has 3 phosphates on it. 2.5. There are 3 RNA polymerases in eukaryotes. RNA pol. II produces mRNA (& snRNA). Pol I and III are for tRNA and rRNA. 7 Modifications of RNA in eukaryotes, Figs. 8.13 & 14. The 5 methlyated cap RNA polymerase may go on for 100s of bases past the signal for the poly-A tail at 3 of the transcript. An enzyme complex cleaves the RNA just downstream of the signal and adds a set of As. Multiple RNA can be transcribed from the same gene in both euk. and prok. 2.6. Splicing out of introns in eukaryotes (see Figs. 8.15-.16). The spliceosome is made of snRNA & proteins. The 5 end of the intron is cut first & folded over to meet a branch point to form a lariat. Then the proteins....
View Full Document

Page1 / 12

nwk2-1 - Elongation: RNA polymerase builds the RNA 2.4....

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online