human phys lec 8 - Autonomicnervoussystem...

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Autonomic nervous system “ egetative“ nervous system Vegetative nervous system Mostly involuntary Neuronal control of organs, glands, and tissues Has sensory and motor (effector) components. Highly amenable to pharmacological intervention Parasympathetic, sympathetic, and enteric branches
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In autonomic motor systems, there are always two synapses in the periphery Peripheral autonomic system Brain or spinal cord Preganglionic axons Parasympathetic ganglion Target tissue Pre Post Sympathetic ganglion Postganglionic axons Target tissue Pre Post
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General organization of peripheral autonomic nervous system mpathetic system CNS Preganglionic cells are cranial Sympathetic system Preganglionic lls are cells are thoracic and lumbar Parasympathetic system Preganglionic gg cells are sacral
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More anatomically realistic depiction of sympathetic ganglia Stellate ganglion Thoracic sympathetic chain ganglion Postganglionic nerve Abdominal aorta Lumbar sympathetic chain ganglion ferior mesenteric ganglion Interganglionic connective Sacral vertebral body Inferior mesenteric ganglion
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Parasympathetic preganglionic nerve fibers easy to find–the vagus nerve vagus Latin verb meaning ‘to wander’
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Structures of large mixed nerves (like the vagus) The vagus is a mixed nerve because parasympathetic preganglionic and viscerosensory fibers both run within it (carrying information in opposite directions)
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Parasympathetic ganglia are small, fragmented, and often imbedded or immediately adjacent to the tissues they control Parasympathetic ganglion adjacent to salivary gland Parasympathetic ganglion imbedded in pancreas Parasympathetic ganglion imbedded in the wall of the bladder
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Principle neurotransmitters in peripheral autonomic systems Parasympathetic ganglion Post ACh ACh Pre N M Sympathetic ganglion Post ACh NE * Pre N A * Sympathetic neurons controlling some eat glands and the seminal vesicles that sweat glands and the seminal vesicles that produce semen use ACh Classic trick question
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The adrenal medulla: A “sympathetic” endocrine gland Ch NE Pre Blood vessels in gland N ACh and EPI M Left adrenal gland Right adrenal gland Right kidney Left kidney
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Different types of neurotransmitter ceptors in autonomic system ACh receptors in sympathetic and parasympathetic ganglia: receptors in autonomic system Nicotinic type ionotropic receptors but slightly different from the ones in skeletal muscle. ACh receptors in target tissues : uscarinic ceptors class of etabotropic ceptors also found in brain Muscarinic receptors , a class of metabotropic receptors also found in brain.
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This note was uploaded on 01/26/2012 for the course BIOL 3324 taught by Professor Ziburkus during the Spring '07 term at University of Houston.

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human phys lec 8 - Autonomicnervoussystem...

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