Unformatted text preview: Metabolically active tissues also affect how the blood carries CO 2 . A small portion of total CO 2 will dissolve directly in the plasma of the blood. About 20 - 25% of the CO 2 carried by the blood will bind to Hb. Low levels of HbO 2 (during activity) enables the Hb to transport more CO 2 , known as the Haldane effect. HbO 2 does not bind to CO 2 as well as deoxyhemoglobin ; so the more O 2 that is unloaded from Hb, the more CO 2 can be bound to Hb. Furthermore, HHb binds more H + than HbO 2 which shifts the CO 2 + H 2 O --> H 2 CO 3--> HCO 3-+ H + reaction to the right enabling an increased conversion of CO 2 into carbonic acid and bicarbonate. The majority of CO 2 produced by the body will be converted into HCO 3-and dissolve in the plasma. This conversion changes the pH of the blood and can alter the respiratory rate....
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- Fall '10
- Anatomy, metabolically active tissues