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Unformatted text preview: alpha types are excitatory while the beta subtypes are inhibitory. In the autonomic nervous system, acetylcholine also binds two types of receptors, the nicotinic acetylcholine receptors and the muscarinic acetylcholine receptors . The nAChR are the familiar type of ACh receptors that are also sodium ion channels and are found on all of the neuronal cell bodies and dendrites in the autonomic ganglia (and at neuromuscular junctions in skeletal muscle). When ACh binds to nAChRs, Na + enters the cell and causes an excitatory depolarization. Thus, nAChRs are excitatory in nature and cause the postganglionic cell to fire an action potential and release NT from its terminal (onto the target). The second type of ACh receptors, the muscarinic receptors, have several subtypes and can be either excitatory or inhibitory. These receptors are found on the glands, smooth muscles and cardiac muscle cells that receives cholinergic innervation....
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- Fall '10