Skeletal System Bone Homeostasis Bone growth and maintenance * Bone is considered never to be at metabolic rest and is constantly being remolded; old bone is being destroyed (osteoclast) and new bone is being laid down (osteoblast). * a delicate balance is created between the osteoblast and osteoclast. * to much new bone tissue causes a condition of bone being abnormally thick and heavy * This process allows for the removal of worn and injured bone and allow for calcium regulation. Normal Bone Homeostasis Depend on Several Factors * adequate mineral: calcium, phosphorus, and magnesium * proper vitamins: A, C, and D * Hormones: human growth hormone, sex hormones (estrogen, testosterone), insulin, thyroid hormones, calcitonin, parathyroid hormone * Exercise that places stress on bones (weight bearing activities) Bone and Mineral Homeostasis * The bones are a rich storage source of calcium and phosphate * calcium is need for muscle and nerve function * phosphorus is needed for proper production of nucleic acids (DNA and RNA) and ATP
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