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Filtration - Urinary System Filtration About 20 of the...

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Urinary System Filtration * About 20% of the plasma that passes through the kidney gets filtered into the nephron * Filtration is takes place in the glomerulus * Driven by the hydrostatic pressure of the blood (osmosis opposes filtration, but the hydrostatic pressure is larger) * Water and small molecules are filtered; blood cells and large molecules (most proteins) do not pass through the filter Filtration Membrane * Kidney trauma and infections can damage the filtration membrane and allow albumin or blood cells to filter through * Proteinuria (albuminuria)- the presence of protein in the urine * Hematuria - the presence of blood in the urine * Strenuous exercise can temporarily cause proteinuria or hematuria * Strenuous exercise greatly reduces perfusion of the kidney causing glomerular deterioration due to prolonged hypoxia. Albuminuria * More than the normal amount of albumin in the urine. Albumin is the predominant protein in human blood and it is the key to the regulation of the osmotic pressure of blood.
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