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Hemopoiesis - or colony-stimulating factors the cells...

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Hemopoiesis Hemopoiesis , the production of new blood cells, is stimulated by a number of chemical messengers in response to alterations in body homeostasis. Embryonically, the hemopoietic tissues include the bone marrow as well as the liver, spleen and thymus. After birth, the liver no longer produces blood cells (although it does produce plasma proteins and therefore contributes to the blood) and the spleen and thymus are only involved in white blood cell maturation. The red bone marrow produces all of the formed elements of the blood: RBCs, WBCs and platelets. Within red bone marrow, hemocytoblasts multiply continually and are pluripotent . In response to stimulation by erythropoietin , thrombopoietin
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Unformatted text preview: or colony-stimulating factors , the cells commit to become one specific cell type. (See Figure 2). Figure 2 Erythrocytes A typical number of erythrocytes in adult females is around 4.2-5.4 million/ uL while for males that number increases to 4.6-6.2 million/uL. RBCs are by far the most important cell type for survival -- a significant drop in RBC count will result in death within minutes. Erythrocytes are responsible for carrying the majority of oxygen to the tissues of the body; the tissues use this oxygen to perform aerobic respiration to make the energy necessary for survival. Reflecting the importance of RBCs, about 2.5 million new RBCs are produced every second ....
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