Unformatted text preview: cell proliferates and differentiates. The resulting cells are clones of the original B-cell and therefore recognize the original antigen. The majority of B-lymphocytes differentiate into plasma cells which secrete antibodies that are specific to the activating antigen; thus the antibodies produced target that antigen. Some differentiated B-cells become memory cells which aggressively and rapidly target for destruction the same antigen if exposure occurs again. (See Figure 7) Figure 7 Antibodies Antibodies bind to the antigen and 1) neutralize the antigen by blocking the pathogenic region of the antigen; 2) "tag" the antigen for destruction by complement protein binding (complement fixation); 3) "tag" the antigen for destruction by phagocytosis; or 4) agglutinate the antigen and immobilize them until phagocytosis....
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- Fall '10
- Anatomy, B cell, Bcell proliferates, original antigen, activating antigen