{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Non - of pathogens into the body The keratinocytes of the...

Info icon This preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Non-Specific Immunity In order to effectively maintain homeostasis, the body must prevent infection by foreign pathogens . Non-specific defenses are effective against a wide range of pathogens and require no prior exposure to the pathogen to be effective. The skin and mucous membranes serve as external barriers that block the entry of pathogens into the body. If invasion or damage does occur, an individual's innate immune system attempts to limit the spread and/or destroy the invaders with phagocytotic cells, antimicrobial proteins, inflammation and fever. External Barriers The best defense against infection is avoiding exposure. The skin is designed to prevent the entry
Image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: of pathogens into the body. The keratinocytes of the skin produces the hard, water-proof protein keratin. The skin is relatively dry and nutrient-poor and perspiration creates an acid mantle on the surface of the skin. Dendritic cells within the epidermis act as phagocytes and resident neutrophils produce defensins to destroy microorganisms. The mucous membranes contain mucus that traps pathogens. Many mucous membranes also produce lysozyme to destroy invading bacteria. The digestive and genitourinary systems prevent microbe invasion with similar methods -- production of mucus and lysozyme and increased acidity. (See Figure 2) Figure 2...
View Full Document

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern