Osseous Cells - removed) and form pits called resorption...

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Osseous Cells Osteogenic cells reside in the endosteum, the inner layer of the periosteum and the central canals . These cells multiply continuously and differentiate into non-dividing osteoblasts in response to stress or fractures (whenever new bone is required). Osteoblasts form and help mineralize the organic matter of the bony matrix; these cells are considered osteocytes when they have become trapped in the matrix they formed. Osteocytes reside in lacunae and are connected to other osteocytes by gap junctions between small cell processes that are found in the canaliculi between lacunae. Although these osteocytes are not continually making bone, they have an important function to signal osteoclasts and osteoblasts about mechanical stresses on the bone. Osteoclasts develop in the red bone marrow by the fusion of 3-50 of the same stem cells that give rise to white blood cells. These cells migrate to damaged areas (or anywhere bone needs to be
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Unformatted text preview: removed) and form pits called resorption bays that they have eaten into the surface of the bone. Extracellular Matrix of Osseous Tissue Bony material is actually a composite material composed of approximately 1/3 organic and 2/3 inorganic matter. The organic matter is composed of collagen, glycosaminoglycans , proteoglycans and glycoproteins. The inorganic matter is mostly hydroxyapatite which is crystallized calcium phosphate. The remainder of the inorganic material is calcium carbonate (10%) and trace amounts of other minerals (fluoride, sulfate, potassium, magnesium). The composite nature of bone provides for both strength and resilience . The mineral components resist compression (provide strength) while the collagen and other proteins resist tension (provides flexibility)....
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This note was uploaded on 01/30/2012 for the course BSC BSC1085 taught by Professor Sharonsimpson during the Fall '10 term at Broward College.

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