Pancreas - intestinal mucosa. * Once trypsin is formed it...

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Digestive System Pancreas: Blood Supply Arteries * small branches from the splenic * superior pancreaticoduodenal - from the gastroduodenal * inferior pancreaticoduodenal - from the superior mesenteric Veins * splenic vein to portal vein * superior mesenteric vein which then becomes the portal vein Pancreatic Enzymes * The pancreas secretes a magnificent battery of enzymes that collectively have the capacity to reduce virtually all digestible macromolecules into forms that are capable of, or nearly capable of being absorbed. Three major groups of enzymes are critical to efficient digestion: * Proteases * Digestion of proteins is initiated by pepsin in the stomach, but the bulk of protein digestion is due to the pancreatic proteases * The two major pancreatic proteases are trypsin and chymotrypsin , which are synthesized and packaged into secretory vesicles as inactive proenzymes trypsinogen and chymotrypsinogen . * Trypsinogen is activated by the intestinal enzyme enterokinase, which is embedded in the
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Unformatted text preview: intestinal mucosa. * Once trypsin is formed it activates chymotrypsinogen, as well as additional molecules of trypsinogen Pancreatic Enzymes * Pancreatic Lipase * A triglyceride molecule cannot be directly absorbed across the intestinal mucosa. * digested into a monoglyceride and free fatty acids. * Sufficient quantities of bile salts must also be present in the lumen of the intestine in order for lipase to efficiently digest dietary triglyceride and for the resulting fatty acids and monoglyceride to be absorbed. Pancreatic Enzymes * Amylase * hydrolyses starch to maltose (a glucose-glucose disaccharide), as well as the trisaccharide maltotriose and small branchpoints fragments called limit dextrins. * Other Pancreatic Enzymes * ribonuclease * deoxyribonuclease * gelatinase * elastase * Bicarbonate and Water Epithelial cells in pancreatic ducts are the source of the bicarbonate and water secreted by the pancreas...
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This note was uploaded on 01/30/2012 for the course BSC BSC1085 taught by Professor Sharonsimpson during the Fall '10 term at Broward College.

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