Stomach1 - producing a different chemical messenger Stomach...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Digestive System Stomach: Glands * Regenerative (stem) cells * Found in the base of the pit and neck of gland * Undergo mitosis to produce new cells * Newly generated cells migrate up as well as downward into the glands to replace cells that die Stomach: Glands * Parietal cell * Found mostly in the upper half of the gland * Secrete HCl and intrinsic factor * Found mostly in the gastric glands, but a few occur in the pyloric glands Stomach: Glands * Chief Cells * Are the most numerous * Secreted in infancy * Chymosin ( also known as rennin)- is a proteolytic enzyme whose role in digestion is to curdle or coagulate milk in the stomach * Lipase- digest the butterfat of milk * pepsinogen * secretes throughout life * Activated to pepsin by HCl * They dominate the lower half of the gastric glands but are absent from cardiac and pyloric glands Stomach: Glands * Enteroendocrine cells * Concentrated especially in the lower half of glands throughout the stomach * Secrete hormones and paracrine messengers that regulate digestion * There are at least eight different kinds of enteroendocrine cells in the stomach, each
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: producing a different chemical messenger Stomach Histology: Stomach * The parietal cells (Oxyntic Cells) are easily seen as large, eosinophilic cells scattered in a background of more basophilic chief cells. * These are very easy to identify because they look like "fried eggs", * the other type of cells are Chief Cells, Histology: Stomach * The parietal cell ( PC ) is large, round, and eosinophilic, thanks to its cytoplasmic complement of mitochondria. Since these cells have a high demand for ATP to drive the pumps that push sodium out of the cytoplasm into the lumen of the stomach, mitochondria are abundant. Digestive System * The chief cell ( CC ) has deeply basophilic basal regions, indicative of the presence of large amounts of RER. At its apical end, the chief cell has granular inclusions; these are the packets of enzymes waiting to be released....
View Full Document

Page1 / 2

Stomach1 - producing a different chemical messenger Stomach...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online