Tight Junctions - tissue Tight Junctions Adherens Junctions...

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tissue Tight Junctions Adherens Junctions * They hold cardiac muscle cells tightly together as the heart expands and contracts. * They hold epithelial cells together. * They seem to be responsible for contact inhibition. * Some adherens junctions are present in narrow bands connecting adjacent cells. * Others are present in discrete patches holding the cells together. Adherens junctions are built from: * cadherins — transmembrane proteins (shown in red) whose * extracellular segments bind to each other and * whose intracellular segments bind to * catenins (yellow). Catenins are connected to actin filaments Gap Junctions * Gap junctions are intercellular channels * These permit the free passage between the cells of ions and small molecules * Because ions can flow through them, gap junctions permit changes in membrane potential to pass from cell to cell. * They are constructed from 4 (sometimes 6) copies of one of a family of a transmembrane proteins called connexins . Desmosomes
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This note was uploaded on 01/30/2012 for the course BSC BSC1085 taught by Professor Sharonsimpson during the Fall '10 term at Broward College.

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Tight Junctions - tissue Tight Junctions Adherens Junctions...

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