Bio171-F08-lec18 - Biology 171 Lecture 18: Monday, October...

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Lecture 18: Monday, October 13, 2008 Biology 171 Today’s Topic: Mendelian Genetics Announcements This Week in Discussion: Genetics problems Exam II – Wed, Oct. 22 Text Reading Lec 18: 2 nd ed: Chapter 13 (269-280) 3 rd ed: Chapter 13 (265-276) Lec 19: 2 nd ed: Chapter 13 (281-297) 3 rd ed: Chapter 13 (281-289) Genetics and Heredity Pre-Mendelian genetics Mendel’s Experimental System Principle of Segregation Principle of Independent Assortment Chromosome Theory of Inheritance Applications for Human Genetics Malaria and Balanced Polymorphisms
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Barack Obama & Dick Cheney - 9 th cousins, once removed Franklin Roosevelt & Sarah Palin - 9 th cousins, once removed Laura Bush & John McCain - 6 th cousins
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Heredity The transmission of traits from one generation to the next. Genetics The scientific study of heredity and of hereditary information Started with the work of Gregor Mendel - an obscure (during his lifetime) 19th century Central European monk. Lets briefly look at pre-Mendelian ideas about heredity
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15,000 years of selective breeding by humans has transformed this magnificent wild predatory mammal into……. Something completely different…. . Domestication of Plants and Animals For thousands of years, humans have selectively bred, to remarkable effect, domesticated plants and animals for desired traits. Take dogs for example.
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There are 400 breeds of dogs; each a targeted product of selective inbreeding
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Preformation Hypothesis : an individual already exists in microscopic form in either the egg ( Ovists ) or sperm ( Spermists ) and only needs to unfold during development. Despite the expertise gained in selective breeding, the underlying nature of heredity remained deeply mysterious*, although it stimulated considerable speculation and many proposed mechanisms. *Remarkably, the conclusive 1952 experimental demonstration that DNA is the hereditary molecule post-dated the 1945 development of nuclear fission and atomic bombs! Spermist Homunculus Hypothesis Blending Inheritance Hypothesis Sperm and eggs of parent organisms contain a sampling of the parent's "essence" that is blended together in the offspring to give an intermediate resultant condition. Yellow
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Bio171-F08-lec18 - Biology 171 Lecture 18: Monday, October...

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