Bio171-F08-lec19 - Biology 171 Lecture 19: Wednesday,...

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Lecture 19: Wednesday, October 20, 2008 Biology 171 Today’s Topic: Complex Patterns of Inheritance Announcements This Week in Discussion: Genetics Problems -Exam II - Wednesday October 22, 6-8PM -Exam review Thursday Oct 16, 6-8 Nat. Sci. Auditorium Text Reading Lec 19: 2 nd ed: Chapter 13 (281-297) 3 rd ed: Chapter 13 (281-289) Lec 20: 2 nd ed: Chapter 24 (516-520; 527-531; 533-536) 3 rd ed: Chapter 25 (503-508; 511-515; 518-520) Corroborating Chromosomal Theory T.H. Morgan - Autosomes & Sex Chromos. Sex-linked Genes Genetic Recombination & Linkage Maps Other Exceptions to Mendelian Inheritance
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BIO 171 Exam II Locations Wednesday, October 22 nd , 6-8 p.m. Aud A Angell Hall Sections: 012, 021, 041, 007, 016, 042, 006, 022, 036 GSIs: Andres, Dieter, Senay Aud D Angell Hall Sections: 005, 010, 014, 033, 039 GSIs: Laury, Dana 1210 Chemistry Sections: 011, 017, 029, 030, 037, 043 GSIs: Susan, Gyorgy 1800 Chemistry Sections: 009, 034, 013, 031, 044, 008, 025, 028, 019, 035, 040, 015, 020, 038 GSIs: Katie, Hannah, Keith, Ed, Devon 1324 East Hall Sections: 023, 026, 032, 018, 024, 027 GSIs: Sean, Peter
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Gregor Mendel (1822-1884)l Mendel’s garden at the monastery in Brno, Czech Republic, where he developed the foundations for the science of Genetics. Like many scientists, Mendel later became an administrator (abbot of the monastery) and made no further scientific contributions!
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Thomas Hunt Morgan 1866-1945; Nobel Prize in 1933 Developed fruit flies ( Drosophila melanogaster ) as a model organism for genetic research Discovery of a mutant male with white eyes Morgan named the gene white , starting the tradition of naming genes after their mutant allele.
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White eye trait is recessive. It reappears in F 2 generation in expected 3:1 ratio. However, it is present in male F 2 flies only 50% of males have red eyes 50% of males have white Test Cross: Female F 1 with white eyed male Result: 50% of females produced have white eyes
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Fruit flies have 4 pairs of chromosomes 3 pairs of equal sized autosomes , (non-sex chromosomes) Each carrying the same genes 1 pair of unequally sized sex chromosomes males are XY, females are XX Pairing of human sex chromosomes during Meiosis in Males: they behave like homologues
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flies resides on the X chromosome and that the Y chromosome does not carry an allele for this gene. This is the hypothesis of X-linked inheritance (or X-linkage ). Females would then have two copies of the gene and males would have only one. Because the mutant genotype is rare and recessive,
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This note was uploaded on 01/30/2012 for the course BIO 171 taught by Professor Josephinekurdziel during the Fall '08 term at University of Michigan.

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Bio171-F08-lec19 - Biology 171 Lecture 19: Wednesday,...

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