VMS 576 Introduction to Veterinary Clinical Research (2 credits) 2012 Syllabus
Designing, executing, analyzing and reporting clinical research fundamental to practicing evidence-based medicine.
The purpose is to develop your understanding of clinical research fundamentals and to coach you
through developing a strong research grant proposal for research that you will carry out under the guidance
of your faculty advisor as a component of your WSU program.
You are expected to obtain your advisor’s guidance and approval throughout the proposal development
process. Near the end of the semester, you will submit this proposal to the VCS Research Committee for
their evaluation of funding worthiness. This evaluation is the primary component of your grade. Because this
scoring is not a ranking, they could score every proposal as fundable, none as fundable, or something in
This proposal may be either for VCS intramural funding or for extramural funding but must meet the
budget and format requirements of the funding source. During the class, you will gain perspective through
providing critical reviews of classmates précis and proposal drafts.
At the end of this class you will:
Understand the components and flow of the scientific research cycle
Use resources supporting literature searches (e.g. Web of Science, PubMed) efficiently and be aware
of bibliographic software (e.g. EndNote, Zotero) options
Develop strong research questions, construct directly testable hypotheses for addressing these, and
strong justifications for your approach.
Select suitable study designs to address these questions, appropriately incorporating key design
components (e.g., randomizing, allocating, blinding, blocking, controlling, replicating) into the design
and avoiding major design and analysis flaws
Apply relevant consensus statements, such as CONSORT, MOOSE, PRISMA, REFLECT, STARD,
STROBE, and MIFlowCyt
Incorporate relevant validated clinical and laboratory standard methods and standard materials,