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Unformatted text preview: ++ ) Balance A. Importance of Ca ++ 1. bone is the "reservoir" of most Ca ++ in the form of Calcium Phosphate (Ca ++ with PO 4-2 ) 2. primary physiological roles (already covered): a. at the muscle and neuron synapse b. essential for blood clotting process c. very critical in heart rhythms B. Ca ++ Regulation: Parathyroid Hormone (PTH) & Calcitonin 1. parathyroid hormone (PTH) - chief control when Ca ++ begins to DECREASE too low a. bones - Ca ++ and PO 4-2 release to blood b. small intestine - activates Vitamin D which is essential for Ca ++ resorption c. kidneys - Ca ++ reabsorbed (but PO 4-2 excreted) Fluid, Electrolyte, Acid/Base Balance 2. calcitonin (thyroid gland) - released when Ca ++ begins to INCREASE too high a. inhibits Ca ++ release from bone, increases actual formation of Calcium Phosphate in bone...
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- Fall '10
- proximal tubule