IV7 - Renal Physiology IV. Tubular Secretion A. Movement...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Renal Physiology IV. Tubular Secretion A. Movement from Capillaries to Tubular Cells 1. K+, creatinine, ammonia, organic acids, drugs 2. Primary functions of tubular secretion: a. moving drugs into the urine b. c. removing excess K+ from blood d. regulating pH (H+ ion removal) V. A. Osmolarity - Number of Solute particles in 1 Liter water 1. independent of size of solute (Na +, glucose) 2. 1 osmol = 6.02 X l0 23 particle in I Liter 3. milliosmol (mosm) = 0.001 osmol 4. normal body fluids = 300 mosm B. Countercurrent Multiplier Mechanism for Maintenance of Blood/Urine Osmolarity 1. Water moves out along Descending Limb of the Loop of Henle, creating 1200 mosm urine at the base 2. Na+Cl- moves out along the Ascending Limb of the Loop of Henle, creating 100 mosm urine at distal end. This salt helps pull more water out of the Descending Limb in positive feedback mechanism. 3.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/29/2012 for the course SCIE SYG2000 taught by Professor Bernhardt during the Fall '10 term at Broward College.

Page1 / 2

IV7 - Renal Physiology IV. Tubular Secretion A. Movement...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online