VI3 - Circulatory Physiology VI. Blood Flow in the Body A....

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Circulatory Physiology VI. Blood Flow in the Body A. General Features 1. delivery of oxygen and removal of carbon dioxide 2. gas exchange in the lungs 3. absorption and delivery of nutrients from GI tract 4. processing/waste removal in the kidneys 5. normal blood flow at rest abdominal organs 24% skeletal muscle 20% kidneys 20% brain 13% heart 4% other 15% B. Velocity of Blood Flow 1. velocity directly related to the TOTAL cross-sectional area of the vessel(s) FASTEST aorta 40-50 cm/s arteries 20-40 cm/s arterioles 1-20 cm/s SLOWEST capillaries 0.1-1 cm/s C. Local Regulation of Blood Flow 1. autoregulation - regulation of blood flow by altering arteriole diameter a. oxygen and carbon dioxide levels b. prostaglandins, histamines, kinins c. needy areas --> more blood flow 2. myogenic response - change in flow through arteriole in response to stretch of smooth muscle 3. reactive hyperemia - increase in blood flow to area where an occlusion has occurred 4. increased vasculature - results from prolonged lack of oxygen/nutrients to
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VI3 - Circulatory Physiology VI. Blood Flow in the Body A....

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