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Unformatted text preview: D. Effects of pH (Acidity) 1. HIGHER pH--> Increased Affinity (left) 2. LOWER pH--> Decreased Affinity (right) "Bohr Effect" a. more Carbon Dioxide, lower pH (more H + ), more O 2 release E. Effects of Diphosphoglycerate (DPG) 1. DPG - produced by anaerobic processes in RBCs 2. HIGHER DPG > Decreased Affinity (right) 3. thyroxine, testosterone, epinephrine, NE - increase RBC metabolism and DPG production, cause RIGHT shift Physiology of Respiration F. Oxygen Transport Problems 1. hypoxia - below normal delivery of Oxygen a. anemic hypoxia - low RBC or hemoglobin b. stagnant hypoxia - impaired/blocked blood flow c. hypoxemic hypoxia - poor lung gas exchange 2. carbon monoxide poisoning - CO has greater Affinity than Oxygen or Carbon Dioxide...
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