lecture 25 - MCB 354 Lecture 3 Glycolysis, Part I Reading...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
MCB 354 Lecture 3 Glycolysis, Part I Reading in Lehninger : Chapter 14
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
GLYCOLYSIS: THE EMBDEN-MEYERHOF PATHWAY (1940s) Glykys + Lysis : “sweet splitting” 6-CARBON TWO 3-CARBON COMPLETE OXIDATION ALSO USES THE TCA OVERALL: SIX CARBONS OF THE REDUCED ORGANIC SUBSTRATE GLUCOSE ARE CONVERTED TO WATER AND CARBON DIOXIDE THE OVERALL GOAL IS TO TRAP THE ENERGY RELEASED IN THESE OXIDATIONS IN A FORM OF CHEMICAL ENERGY THAT CAN BE USED LATER BY THE ORGANISM THE ENERGY CURRENCIES ARE: ATP, NADH AND ACETYL-CoA ANAEROBIC OXIDATION YIELDS LESS ENERGY TRAPPED IN A USEFUL FORM 3-1
Background image of page 2
WHY GLUCOSE? 3-2 GLUCOSE IS FORMED FROM FORMALDEHYDE UNDER PREBIOTIC CONDITIONS MOST STABLE HEXOSE: SUBSTITUENTS AXIAL IN PYRANOSE LOW POTENTIAL FOR NON-ENZYMATIC PROTEIN GLYCOSYLATION EXISTS AN UNREACTIVE PYRANOSE (HEMIACETAL) WHEN THE OPEN FORM OF THE SUGAR IS NEEDED, ENZYMES WILL OPEN THE RING SYSTEM)
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
GLYCOLYSIS HAS TWO PHASES PREPARATORY PHASE: ENERGY IS USED 3-3
Background image of page 4
GLYCOLYSIS HAS TWO PHASES PAYOFF PHASE: ENERGY IS GENERATED 3-4
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
STEP #1: GLUCOSE -> GLUCOSE 6-PHOSPHATE PHOSPHORYL GROUP TRANSFER PHOSPHORYL GROUPS ACT AS “HANDLES” FOR MOLECULAR RECOGNITION BY ENZYMES AND PROVIDE INCREASED BINDING
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/29/2012 for the course MCB 354 taught by Professor Spees during the Spring '09 term at University of Illinois, Urbana Champaign.

Page1 / 30

lecture 25 - MCB 354 Lecture 3 Glycolysis, Part I Reading...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online