lecture 29 - MCB 354 Lecture 7 Tricarboxylic Acid Cycle,...

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MCB 354 Lecture 7 Tricarboxylic Acid Cycle, Part I Reading in Lehninger : Chapter 16
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THE FATES OF PYRUVATE CRITICAL FOR THE REGENERATION OF NAD+ AEROBIC ANAEROBIC AEROBIC METABOLISM TCA CYCLE COMMON INPUT FEEDPOINT 7-1
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THE TCA (KREBS) CYCLE THE TCA CYCLE TAKES THE TWO CARBONS OF ACETYL CoA AND OXIDIZES THESE PRODUCING TWO CARBON DIOXIDE MOLECULES 7-3
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THE TCA CYCLE: OVERALL “FLOW” NOTE THE COMMON INPUT POINT AT ACETYL-CoA CARBONS ARE OXIDIZED TO CARBON DIOXIDE WITH PRODUCTION OF REDUCING EQUIVALENTS WHICH ENTER THE ET CHAIN 7-4
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THE TCA CYCLE OCCURS IN MITOCHONDRIA. OF LEHNINGER FAME 7-2
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THE TCA CYCLE OCCURS IN MITOCHONDRIA. OF LEHNINGER FAME 7-2
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THE TCA CYCLE OCCURS IN MITOCHONDRIA. OF LEHNINGER FAME 7-17 Acetyl-CoA: substrate OAA: “catalyst” but released CO2 is derived from OAA Carbons from acetyl- CoA are incorporated into OAA and eventually released as CO2 Note that succinate is symmetrical: scrambles carbon from acetyl-CoA
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THE TCA (KREBS) CYCLE THE FIRST STEP IS TO CONVERT PYRUVATE TO ACETYL CoA ACETYL CoA IS FORMED FROM GLYCOGEN, FATS AND SOME AMINO ACIDS 7-5
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lecture 29 - MCB 354 Lecture 7 Tricarboxylic Acid Cycle,...

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