topic 3_rivier_252 - MCB 252 Cell Biology, part 2 Topic 3...

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MCB 252 Cell Biology, part 2 Topic 3 Role of Actin in Cell Movement
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Reading Reading 1: Lodish 17.0- 17.2
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MCB 252 Actin Cytoskeleton A. Properties of Actin B. Role of Actin in Cell Movement C. Regulation of Actin Assembly in Cells D. Stable Actin Structures E. Muscle Cells and Myosin Motors
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Actin Cytoskeleton Properties of Actin Actin assembly Role of ATP Treadmilling Role of actin in cell movement Actin is required for movement Actin assembly can drive movement Regulation of actin assembly in cells Proteins invovled in actin assembly/disassembly Turning the protein invovled in assembly and disassembly ON and OFF
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Actin Polymarization Can Do Work G-actin -> F-actin + released energy Released energy can do work Work can result in membrane extension (Membrane extension requires work) G-actin -> F-actin + membrane extension
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Actin: stable structures and dynamic structures
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polymerization is required for migration? Two experimental questions:
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This note was uploaded on 01/29/2012 for the course MCB 252 taught by Professor Wuebbles during the Spring '08 term at University of Illinois, Urbana Champaign.

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topic 3_rivier_252 - MCB 252 Cell Biology, part 2 Topic 3...

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