topic 11_rivier_252 - MCB 252 Topic 11 Motors in Mitosis...

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Unformatted text preview: MCB 252 Topic 11 Motors in Mitosis Reading: Lodish 18-6 Roles of MTs in Interphase and Mitosis In Mitosis: 1.Cease Interphase Roles: Organelle transport and positioning 2. New Role: Attach to, Position, and Move Chromosomes Roles of MTs in Interphase and Mitosis What Happens During this Transition? Events in Mitosis Interphase/prophase Mitosis Fig. 12.5 DNA Compaction: Spaghetti in a Sailboat 2 x 3 x 109 bp x .34 nm/bp = 2 meters DNA/nucleus Scale by 1,000,000: Nucleus 10m 10 meter sailboat DNA diameter 2 nm 2 millimeter DNA length 2 meters 2000 kilometers (1200 miles) UIUC to Orlando, Florida = 1066 miles Events in Mitosis Events in Mitosis, part 2 Roles of MTs in Interphase and Mitosis In Mitosis: 1.Cease Interphase Roles: Organelle transport and positioning 2. New Role: Attach to, Position, and Move Regulation of Dynamic Instability in Mitosis Balance of MAPs v. Catastrophe Factors -> Dynamics Increased Gamma-TURC at centrosomes Three Classes of Mitotic Microtubules Kinetochore, Polar and Astral Chromosome Segregation- General Features...
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This note was uploaded on 01/29/2012 for the course MCB 252 taught by Professor Wuebbles during the Spring '08 term at University of Illinois, Urbana Champaign.

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topic 11_rivier_252 - MCB 252 Topic 11 Motors in Mitosis...

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