DNA Translatio2 - DNA Translation Ribosomes After...

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DNA Translation Ribosomes After post-transcriptional processing , mRNA leaves the cell nucleus and bonds with a ribosome, a structure composed of proteins and RNA (rRNA) that assists in the binding process between mRNA codons and tRNA anticodons. While ribosome can only work on one mRNA strand at a time, multiple ribosomes can bind to any mRNA strand to form polyribosomes. Eukaryotic and prokaryotic ribosomes differ slightly in their size and complexity, though their function is generally similar. Until we discuss the specific properties of eukaryote translation , we will talk only about prokaryote translation. Ribosome Structure Ribosomes are composed of two subunits, one small and one large. Four binding sites are located on the ribosome, one for mRNA and three for tRNA. The three tRNA sites are labeled P, A, and E. The P site, called the peptidyl site, binds to the tRNA holding the growing polypeptide chain of amino acids. The A site (acceptor site), binds to the aminoacyl tRNA, which holds the new
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This note was uploaded on 01/27/2012 for the course BIOLOGY BSC1005 taught by Professor Rodriguez during the Winter '09 term at Broward College.

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DNA Translatio2 - DNA Translation Ribosomes After...

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