DNA Translation - DNA Translation The Mechanism of...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
DNA Translation The Mechanism of Translation Translation involves three steps: 1. Initiation 2. Elongation 3. Termination Initiation Translation begins with the binding of the small ribosomal subunit to a specific sequence on the mRNA chain. The small subunit binds via complementary base pairing between one of its internal subunits and the ribosome binding site, a sequence of about ten nucleotides on the mRNA located anywhere from 5 and 11 nucleotides from the initiating codon, AUG. Figure %: Initiation Once the small subunit has bound, a special tRNA molecule, called N-formyl methionine, or fMet, recognizes and binds to the initiator codon. Next, the large subunit binds, forming what is known as the initiation complex. With the formation of the initiation complex, the fMet-tRNA occupies the P site of the ribosome and the A site is left empty. This entire initiation process is facilitated by extra proteins, called initiation factors that help with the binding of ribosomal subunits and tRNA to the mRNA chain. Termination
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 2

DNA Translation - DNA Translation The Mechanism of...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online