Case Study - IBD - Inflammatory Bowel Disease Case Study...

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Inflammatory Bowel Disease Case Study Danielle is a 28 year old mother of two young children with complaints of frequent episodes of diarrhea, GI cramping, weight loss and fatigue. She is also a regular user of ibuprofen for neck and back pain. An examination of her GI track reveals cobblestoning in the distal ileum and sigmoid colon. Biopsies of the inflamed areas are taken and sent to the lab for testing. 1. Of the two IBDs discussed in class, which one does Danielle have? Support your answer with at least two distinguishing features. Diagnosis: ____ Crohn`s disease __________________ Distinguishing Features: ___ Cobblestoning __________ ___ fatigue (bloody stool anemia) __ 2. Identify the environmental risk factor that may have predisposed Danielle to this flare-up? Provide the mechanism. Environmental Trigger: ___ NSAID (Ibuprofen) _______________________ Mechanism: ______ COX 2 Pathway (uncontrolled inflammation)_ 3. Which type of helper T-cell lymphocyte is expected to be elevated in the biopsied
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This note was uploaded on 01/28/2012 for the course NS 441 taught by Professor Caudill during the Fall '11 term at Cornell University (Engineering School).

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Case Study - IBD - Inflammatory Bowel Disease Case Study...

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