Diabetes IV Summary - Fuel source Muscle protein Alanine,...

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Diabetes IV Respond to the following: - Compared to people without diabetes, people with diabetes should: (a) Restrict carbohydrate intake (b) Increase protein intake i. Recommendation : 15- 20 % of total kcal (NORMAL) (c) Limit fat intake Appreciate the utility of low glycemic index (GI) foods Starvation and Stress Early starvation Adapted (late)starvation Stress/sepsis/trauma Hormones Catabolic hormones Cortisol / epinephrine Glucagon Insulin ↓↓ Cortisol ↓ Glucagon Epinephrine Insulin (needed for “healing” proteins)
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Unformatted text preview: Fuel source Muscle protein Alanine, glutamate Adipose tissues (FA) Glycerol Ketone (all tissues) AA (muscle protein) Metabolic pathway LIVER Glycogenolysis Gluconeogenesis Gluconeogenesis (glycer ol) Ketone bodies (severe in T1DM) Proteolysis (loss of lean tissue) Insulin resistant (muscle) Diabetes IV Glutamine (neutralize pH) (Injection) Role of Alanine/Lactate Pyruvate Alanine Lactate Lactate Reduced (glycerol main) Muscle not broken down Similar to early starvation? SUMMARY...
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This note was uploaded on 01/28/2012 for the course NS 441 taught by Professor Caudill during the Fall '11 term at Cornell University (Engineering School).

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Diabetes IV Summary - Fuel source Muscle protein Alanine,...

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