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Unformatted text preview: voluntary muscles. Therefore, it mediates all voluntary movement. Every move that we make depends on acetylcholine released to our muscles by motor neurons. When acetylcholine is released, it causes depolarization of the muscle membrane and will also cause the muscle to contract.Therefore, if the effects of acetylcholine were not limited, then our muscles would continue to contract without the ability to relax and would result in generalized muscle cramping, spasms, and seizures. Also, because the muscle cell membrane would not be able to repolarize for renewed contractions, it would lead to generalized paralysis. Acetylcholine also contributes to attention, arousal, and memory. This is why memory loss seen in Alzheimer's disease is associated with an inadequate supply of acetylcholine in certain areas of the brain. The drug treatments for the disease amplify acetylcholine activity and can slightly slow the progress of the disease....
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- Fall '08