lecture33_Digestive3and4

lecture33_Digestive3and4 - Digestive System III and IV...

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Unformatted text preview: Digestive System III and IV Review of the Digestive Organs Mouth and Salivary Glands Pharynx and Esophagus Stomach duodenum jejunum ileum secum appendix colon rectum Large Intestine pancreas liver Small Intestine Pancreatic and Biliary Secretions Pancreas and Liver- provide secretions that mix with the contents of the duodenal lumen ancreas- located behind and below the stomach- mixed gland the contains both exocrine and endocrine tissue exocrine portion :-- acinar cells- release 3 types of enzymes 1) 2) 3) proteolytic enzymes- for protein digestion pancreatic amylase- for carbohydrate digestion pancreatic lipase- for fat digestion Pancreatic and Biliary Secretions Pancreas and Liver- provide secretions that mix with the contents of the duodenal lumen ancreas- located behind and below the stomach- mixed gland the contains both exocrine and endocrine tissue exocrine portion :-- acinar cells- release 3 types of enzymes 1) 2) 3) duct cells- release sodium bicarbonate (NaHCO 3 ) proteolytic enzymes- for protein digestion pancreatic amylase- for carbohydrate digestion pancreatic lipase- for fat digestion roteolytic enzymes secreted by pancreas - 3 major types 1) 2) 3) ancreatic Secretions (cont.) trypsinogen chymotrypsinogen procarboxypeptidase released as inactive forms that are not activated until reach duodenum (to prevent self digestion) nterokinase- enzyme in luminal border of duodenum that converts trypsinogen into trypsin (active form). Trypsin can then autocatalytically trigger further conversion. rypsin inhibitor- a substance in pancreas that blocks trypsin in case trypsinogen inadvertently converts to trypsin prematurely Trypsin converts - chymotrypsinogen chymotrypsin- procarboxypeptidase carboxypeptidase active form ancreatic Secretions (cont.) ancreatic Amylase- contributes to carbohydrate digestion- secreted as an active form because active amylase can not injure secretory cells- extremely important because it is the only ancreatic Lipase enzyme secreted in the digestive tract that can digest fat lkaline environment - all of the pancreatic enzymes work best in an alkaline environment- duct cells contribute to neutralizing the acidic chyme by releasing sodium bicarbonate (NaHCO 3 ) Pancreatic Secretions (cont.) Pancreatic secretions are hormonally regulated hyme- in the duodenum triggers the release of 2 major enterogastrones-- Secretin- release triggered primarily by acidic chyme Pancreatic Secretions (cont.) Pancreatic secretions are hormonally regulated hyme- in the duodenum triggers the release of 2 major enterogastrones...
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This note was uploaded on 01/29/2012 for the course NPB 101 taught by Professor Fuller,charles/goldberg,jack during the Winter '08 term at UC Davis.

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lecture33_Digestive3and4 - Digestive System III and IV...

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