lecture22_Cardio5

lecture22_Cardio5 - Cardiovascular Physiology V...

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Cardiovascular Physiology V (Circulation and Blood Pressure—part 2) Reading : chapter 10, pgs 358-365
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Pressure - often measured in units of mm of Hg. - - example, ventricular pressure during systole may reach 120 mm Hg. 120 mm Hg is the pressure exerted beyond atmospheric pressure (which is 760 mm Hg) next slide .
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Atmospheric Pressure : The pressure exerted on objects by the atmospheric air above the earth’s surface at sea level can push a column of mercury to a height of 760 mm. Therefore, atmospheric pressure at sea level is considered to be 760 mm Hg.
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Extrinsic control - factors extrinsic to an organ or tissue that control arteriolar radius. - - Arterioles sympathetic control - - - Both neural and hormonal factors can influence the total peripheral resistance to blood flow. Can be counteracted by local chemical and physical influences. acts through norepinephrine (NE) release to contract arteriolar smooth muscle, thus leading to vasoconstriction. the action of NE is mediated by alpha ( α ) adrenergic receptors on the arteriolar smooth muscle cells. action of NE can be overridden by local metabolic controls.
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Epinephrine and Norepinephrine : Extrinsic control - (cont.) Hormonal Control: - These hormones are released from the adrenal medulla in response to sympathetic stimulation
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lecture22_Cardio5 - Cardiovascular Physiology V...

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